山口大学 共同獣医学部

教員紹介

獣医内科学研究室 下川 孝子 (TAKAKO SHIMOKAWA, PhD, DVM)

 

助教
獣医内科学分野

e-mail: tshimo@yamaguchi-u.ac.jp
Tel: 083-933-5823
Fax: 083-933-5823

http://web.cc.yamaguchi-u.ac.jp/~vintmed/index.html

担当授業科目

獣医内科学実習 臨床実習

詳細は修学支援システムへ

研究テーマ

・犬における持続的腎代替療法に関する研究
・難治性免疫介在性疾患に対する血液浄化療法の臨床応用

主な研究業績

・Domori A, Sunahara A, Tateno M, Shimokawa Miyama T, Setoguchi A, Endo Y. The clinical utility of two human portable blood glucose meters in canine and feline practice. Vet Clin Pathol. 2013 (In press).

・Tateno M, Nishio T, Matsuo T, Sakuma M, Nakanishi N, Izawa M, Asari Y, Okamura M, Shimokawa Miyama T, Setoguchi A, Endo Y. Epidemiological survey of tick-borne protozoal infection in Iriomote cats and Tsushima leopard cats in Japan. J Vet Med Sci. 2013 July; 75:985 – 989.

・Tateno M, Nishio T, Sakuma M, Nakanishi N, Izawa M, Asari Y, Okamura M, Maruyama S, Shimokawa Miyama T, Setoguchi A, Endo Y. Molecular epidemiological survey of Bartonella, Ehrlichia and Anaplasma infections in Japanese Iriomote and Tsushima leopard cats. J Wildl Dis. 2013 July; 49:646 – 652. [doi: 10.7589/ 2012- 07-194].

・Hirata M, Tateno M, Sakuma M, Nakanishi N, Izawa M, Asari Y, Okamura M, Shimokawa Miyama T, Setoguchi A, Endo Y. An epidemiological survey of hemoplasma infection in Iriomote cats (Prionailurus bengalensis iriomotensis). J Vet Med Sci. 2012 Dec; 74:1531-1537.

・Sakuma M, Fukuda K, Takayama K, Kobayashi Y, Shimokawa Miyama T, Setoguchi A, Endo Y. Molecular epidemiological survey of the Babesia gibsoni cytochrome b gene in western Japan. J Vet Med Sci. 2012 Oct; 74:1341-1344.

・Shimokawa Miyama T, Umeki S, Baba K, Sada K, Hiraoka H, Endo Y, Inokuma H, Hisasue M, Okuda M, Mizuno T. Neutropenia associated with osteomyelitis due to Hepatozoon canis infection in a dog. J Vet Med Sci. 2011 Jun; 73:1389-1393.

・Sakuma M, Nishio T, Nakanishi N, Izawa M, Asari Y, Okamura M, Shimokawa Miyama T, Setoguchi A, Endo Y. A case of Iriomote cat (Prionailurus bengalensis iriomotensis) with Hepatozoon felis parasitemia. J Vet Med Sci. 2011 Oct; 73:1381-1384.

・Okawa T, Yanase T, Shimokawa Miyama T, Hiraoka H, Baba K, Tani K, Okuda M, Mizuno T. Prekallikrein deficiency in a dog. J Vet Med Sci. 2011 Jan; 73:107-111.

・Shimokawa Miyama T, Itamoto K, Yoshioka C, Minami K, Okawa T, Fujisaki Y,Hiraoka H, Mizuno T, Okuda M. Evaluation of the hemodynamic impact of continuous renal replacement therapy in healthy dogs. J Vet Med Sci. 2010 Apr; 72:493-497.

・Shimokawa Miyama T, Yoshioka C, Minami K, Okawa T, Hiraoka H, Itamoto K, Mizuno T, Okuda M. Nafamostat mesilate is not appropriate as an anticoagulant during continuous renal replacement therapy in dogs. J Vet Med Sci. 2010 Mar; 72:363-367.

・Shimokawa Miyama T, Iwamoto E, Umeki S, Nakaichi M, Okuda M, Mizuno T. Magnetic resonance imaging and clinical findings in a miniature Schnauzer with hypodipsic hypernatremia. J Vet Med Sci. 2009 Oct; 71:1387-1391.

・Hiraoka H, Minami K, Kaneko N, Shimokawa Miyama T, Okamura Y, Mizuno T, Okuda M. Aberrations of the FHIT gene and Fhit protein in canine lymphoma cell lines. J Vet Med Sci. 2009 Jun; 71:769-777.

・Hiraoka H, Minami K, Kaneko N, Shimokawa Miyama T, Mizuno T, Okuda M. Molecular cloning of the canine fragile histidine triad (FHIT) gene and Fhit protein expression in canine peripheral blood mononuclear cells. J Vet Med Sci. 2009 May; 71:645-649.

・Kaneko N, Yamamoto Y, Wada Y, Shimokawa Miyama T, Hiraoka H, Itamoto K, Mizuno T, Nakaichi M, Takahashi T, Watari T, Okuda M. Application of polymerase chain reaction to analysis of antigen receptor rearrangements to support endoscopic diagnosis of canine alimentary lymphoma. J Vet Med Sci.2009 May; 71:555-559.

・Kaneko N, Tanimoto T, Morimoto M, Hayashi T, Shimokawa Miyama T, Hiraoka H, Itamoto K, Une S, Mizuno T, Okuda M. Use of formalin-fixed paraffin-embedded tissue and single-strand conformation polymorphism analysis for polymerase chain reaction of antigen receptor rearrangements in dogs. J Vet Med Sci. 2009 Apr; 71:535-538.

・Hiraoka H, Hisasue M, Nagashima N, Miyama T, Tanimoto T, Watanabe M, Itamoto K, Mizuno T, Inokuma H. Okuda M. A dog with myelodysplastic syndrome: chronic myelomonocytic leukemia. J Vet Med Sci. 2007; 69:665-668.

・Miyama T, Inokuma H, Itamoto K, Okuda M, Verdida RA, Xuan X. Clinical usefulness of antibodies against Babesia gibsoni detected by ELISA with recombinant P50. J Vet Med Sci. 2006; 68:1371-1373.

・杉村肇、坂口真也、今村圭太、見山孝子、板本和仁、奥田 優、島田洋二郎、坂田義美、猪熊 壽. 犬糸状虫症感染予防に来院した犬のバベシア、ヘモバルトネラおよびエールリヒア感染状況調査. 日獣会誌. 2006; 59: 267- 270.

・Taroura S, Shimada Y, Sakata Y, Miyama T., Hiraoka H, Watanabe M, Itamoto K, Okuda M, Inokuma H. Detection of DNA of 'Candidatus Mycoplasma haemominutum' and Spiroplasma sp. in unfed ticks collected from vegetation in Japan. J Vet Med Sci. 2005; 67:1277-1279.

・Miyama T, Sakata Y, Shimada Y, Ogino S, Watanabe M, Itamoto K, Okuda M, Verdida RA, Xuan X, Nagasawa H, Inokuma H. Epidemiological survey of Babesia gibsoni infection in dogs in eastern Japan. J Vet Med Sci. 2005; 67:467-471.

・Inokuma H, Okuda M, Yoshizaki Y, Hiraoka H, Miyama T, Itamoto K, Une S, Nakaichi M, Taura Y. Clinical observations of Babesia gibsoni infection with low parasitaemia confirmed by PCR in dogs. Vet Rec. 2005; 156:116-118.

・平岡博子、見山孝子、白永伸行、中市統三、渡邊麻麗香、板本和仁、奥田 優、猪熊 壽. 脾臓摘出後に発症した犬ヘモバルトネラ症の1例. 日獣会誌. 2004; 57: 587- 590.

研究内容の紹介

 小動物臨床の現場には病態解明が十分でなく、診断・治療法も確立されていない難治性疾患が数多く存在しています。このような疾患のブレイクスルーとなるような治療法の確立をめざした研究を行っています。特に致死率の高い全身性炎症反応症候群や敗血症、急性腎不全や治療困難な免疫介在性疾患に対して、持続的腎代替療法をはじめとする血液浄化療法を用いた治療法の確立を目指して研究を行っています。

コンタクトインフォメーション

居室:連合獣医3階

オフィスアワー:随時