山口大学 共同獣医学部

教員紹介

病態制御学講座 下田 宙 (HIROSI SHIMODA, DVM, PhD)

准教授
獣医微生物学分野

e-mail: hshimoda@yamaguchi-u.ac.jp
Tel&FAX: 083-933-5888

http://web.cc.yamaguchi-u.ac.jp/~vetmicro/html/

担当授業科目

獣医微生物学 獣医微生物学免疫学実習
   
 

詳細は修学支援システムへ

研究テーマ

・様々な動物におけるウイルス診断法の確立
・国内外の野生動物におけるウイルス感染症の疫学的調査
・野生動物、伴侶動物、生産動物、節足動物における節足動物媒介ウイルス感染症の調査

主な研究業績

1. Ohtani A, Kubo M, Shimoda H, Ohya K, Iribe T, Ohishi D, Endoh D, Omatsu T, Mizutani T, Fukushi H, Maeda K. Genetic and Antigenic Analysis of Chlamydia pecorum Strains Isolated from Calves with Diarrhea. Journal of Veterinary Medical Science (In press)

2. Andoh K, Hattori S, Moumoud HYAM, Takasugi M, Shimoda H, Bannai H, Tsujimura K, Matsumura T, Kondo T, Kirisawa R, Mochizuki M, Maeda K. The haemagglutination activity of equine herpesvirus type 1 glycoprotein C. Virus Research 2015 Jan 2; 195:172-176.

3. Terada Y, Matsui N, Noguchi K, Kuwata R, Shimoda H, Soma T, Mochizuki M, Maeda K. Emergence of pathogenic coronaviruses in cats by homologous recombination between feline and canine coronaviruses. PLoS ONE 2014 Sep 2;9(9):e106534.

4. Shimojima M, Takenouchi A, Shimoda H, Kimura N, Maeda K. Distinct usage of three C-type lectins by the Japanese encephalitis virus: DC-SIGN, DC-SIGNR, and LSECtin. Archives of Virology 2014 Aug;159(8):2023-31.

5. Shimoda H, Saito A, Noguchi K, Terada Y, Kuwata R, Akari H, Takasaki T, Maeda K. Seroprevalence of Japanese encephalitis virus infection in captive Japanese macaques (Macaca fuscata). Primates. 2014 Jul;55(3):441-445. doi: 10.1007/s10329-014-0421-7. Epub 2014 Apr 19.

6. Hara Y, Terada Y, Yonemitsu K, Shimoda H, Noguchi K, Suzuki K, Maeda K. High prevalence of hepatitis E virus in wild boar in Yamaguchi Prefecture, Japan. Journal of Wildlife Diseases 2014;50(2):378–383.

7. Terada Y, Minami S, Noguchi K, Mahmoud H.Y.A.H., Shimoda H, Mochizuki M, Une Y, Maeda K. Genetic characterization of coronaviruses from domestic ferrets in Japan. Emerging Infectious Diseases 2014 Feb;20(2):284-287.

8. Hwang CC, Umeki S, Kubo M, Hayashi T, Shimoda H, Mochizuki M, Maeda K, Baba K, Hiraoka H, Coffey M, Okuda M, Mizuno T. Oncolytic reovirus in canine mast cell tumor. PLoS One. 2013 Sep 20;8(9):e73555.

9. Mahmoud HY, Andoh K, Hattori S, Terada Y, Noguchi K, Shimoda H, Maeda K. Characterization of Glycoproteins in Equine Herpesvirus-1. Journal of Veterinary Medical Science 2013 Oct 31;75(10):1317-21.

10. Hara Y, Suzuki J, Noguchi K, Terada Y, Shimoda H, Mizuno T, Maeda K. Function of feline signaling lymphocyte activation molecule as a receptor of canine distemper virus. Journal of Veterinary Medical Science 2013 75(8):1085-1089.

11. Shimoda H, Mahmoud HYAH, Noguchi K, Terada Y, Takasaki T, Shimojima M, Maeda K. Production and characterization of monoclonal antibodies to Japanese encephalitis virus. Journal of Veterinary Medical Science 2013 75(8):1077-1080.

12. Andoh K, Takasugi M, Mahmoud HYAH, Hattori S, Terada Y, Noguchi K, Shimoda H, Bannai H, Tsujimura K, Matsumura T, Kondo T, Maeda K. Identification of a major immunogenic region of equine herpesvirus-1 glycoprotein E and its application to enzyme-linked immunosorbent assay. Veterinary Microbiology 2013 May 31;164(1-2):18-26.

13. Noguchi K, Shimoda H, Terada Y, Shimojima M, Kohyama K, Inoshima Y, Maeda K. Isolation of a novel herpesvirus from a Pacific white-sided dolphin. Archives of Virology 2013 158(3): 695-699.

14. Shimoda H, Inthong N, Noguchi K, Terada Y, Nagao Y, Shimojima M, Takasaki T, Rerkamnuaychoke W, Maeda K. Development and application of an indirect enzyme-linked immunosorbent assay for serological survey of Japanese encephalitis virus infection in dogs. Journal of Virological Methods 2013 Jan;187(1):85-89.

15. Terada Y, Shiozaki Y, Shimoda H, Mahmoud HYA, Noguchi K, Nagao Y, Shimojima M, Iwata H, Mizuno T, Okuda M, Morimoto M, Hayashi T, Tanaka Y, Mochizuki M, Maeda K. Feline infectious peritonitis virus with a large deletion in the 5' terminal region of spike gene retains its virulence for cats. Journal of General Virology 2012 93: 1930-1934.

16. Nagao Y, Nishio Y, Shimoda H, Tamaru S, Shimojima M, Goto M, Une Y, Sato A, Ikebe Y, Maeda K. An outbreak of canine distemper virus in tigers (Panthera tigris): Possible transmission from wild animals to zoo animals. Journal of Veterinary Medical Science 2012 74(6): 699-705.

17. Shirato K†, Maeda K†, Tsuda S†, Suzuki K, Watanabe S, Shimoda H, Ueda N, Iha K, Taniguchi S, Kyuwa S, Endoh D, Matsuyama S, Kurane I, Saijo M, Morikawa S, Yoshikawa Y, Akashi H, Mizutani T. Detection of bat coronaviruses from Miniopterus fuliginosus in Japan. Virus Genes. 2012 Feb;44(1):40-44.(†Equally contributed)

18. Kameo Y†, Nagao Y†, Nishio T, Shimoda H, Nakano H, Suzuki K, Une Y, Sato H, Shimojima M, Maeda K. Epizootic canine distemper virus infection among wild mammals. Veterinary Microbiology 2012, 154(3-4): 222-229. (†Equally contributed)

19. Shimoda H, Nagao Y, Shimojima M, Maeda K: Viral infectious diseases in wild animals in Japan. Journal of Disaster Research 2012. 7(3): 289-296.

20. Shimoda H, Tamaru S, Morimoto M, Hayashi T, Shimojima M, Maeda K. Experimental infection of Japanese encephalitis virus in dogs. Journal of Veterinary Medical Science 2011 Sep 30;73(9):1241-1242.

21. Shimojima M†, Nagao Y†, Shimoda H, Tamaru S, Yamanaka T, Matsumura T, Kondo T, Maeda K. Full genome sequence and virulence analyses of the recent equine isolate of Japanese encephalitis virus. Journal of Veterinary Medical Science 2011, Jun;73(6):813-816. (†Equally contributed)

22. Watanabe S†, Maeda K†, Suzuki K, Ueda N, Iha K, Taniguchi S, Shimoda H, Kato K, Yoshikawa Y, Morikawa S, Kurane I, Akashi H, and Mizutani T. Novel betaherpesvirus in bats. Emerging Infectious Diseases.2010, 16(6): 986-988.(†Equally contributed)

23. Shimoda H, Ohno Y, Mochizuki M, Okuda M, Iwata H, Maeda K. Dogs as sentinels for human infection with Japanese encephalitis virus. Emerging Infectious Diseases. 2010 Jul;16(7):1137-1139.

研究内容の紹介

 人獣共通感染症として公衆衛生上重要な節足動物媒介ウイルス感染症の国内外における実態を明らかにするために伴侶動物(イヌ・ネコ)や野生動物(コウモリ・イノシシ・シカ)における疫学調査およびその調査手法の開発を中心に研究を進めています。
 また、コウモリなどの野生動物由来の感染症は世界各地で頻発しており、それら国内外の動物由来ウイルス感染症の実態把握・予防法の確立を目指し、国内外の野生動物を対象に疫学的研究を実施しています。

コンタクトインフォメーション

居室:共同獣医部3階304号室

オフィスアワー:随時